Empirically, it is considered that absolute zeta potential values higher than ± 30 mV are indicative of stable dispersions. The zeta potential of particles is a key indicator of the stability of a colloidal dispersion, like nanoparticles or liposomes, since it reflects the ability of particles to repulse each other electrostatically. Knowledge of the zeta potential of a material helps you optimize specific surface modification processes for a material to perform at its best when applied. membranes for water treatment, biomaterials in contact with blood, or wet processing of semiconductor wafers. The zeta potential of macroscopic surfaces is thus important for understanding the behavior of solid materials in many technical processes in which aqueous systems play a role, e.g. Measuring the zeta potential provides information on surface functionality, the stability of dispersed particles as well as interaction of dissolved compounds with the solid surface. A surface charge can be observed for solid materials (solid-liquid interface) as well as liquid droplets (liquid-liquid interface).The properties of the liquid medium play an important role in the formation of the zeta potential, which is highly dependent on the pH value or buffer concentration.However, the differentiation is important in order to choose the right technology to measure the zeta potential. membranes, hair, polymers) as well as from particles dispersed in a liquid (e.g. The zeta potential can be measured on macroscopic surfaces (e.g.It represents the effective net charge in this condition. The zeta potential is only present if a material comes in contact with a liquid.The following needs to be kept in mind when talking about zeta potential: The zeta potential is defined as the sum of the initial surface charge and the accumulated layer. These counter ions arrange themselves spontaneously in a so-called electrochemical double layer. This process results in a surface charge, which attracts the accumulation of oppositely charged ions. If a material comes in contact with a liquid, the functional groups on its surface will react with the surrounding medium. The zeta potential (also known as electrokinetic potential) is established on the surface of any material when it comes in contact with a liquid medium.